β Quick Highlights
- Medicine: Metrex
- Formula: Metholrexate
- Dosage: 2.5mg per tablet
- Quantity: 100 Tablets
- Price: Rs. 6,500/-
- Result: 100% Effective
- Shipping: Free Home Delivery (1β3 days)
- Origin: Imported / Korea
- Manufactured: DAEHAN NEW PHARM
- Quality Specification: USP
Complete Guide to Metrex Tablets (Methotrexate 2.5 mg) in Pakistan
Metrex Tablets, containing Methotrexate 2.5 mg, are among the most prescribed medicines in Pakistan for autoimmune diseases such as rheumatoid arthritis (RA), psoriasis, and certain cancers. Their affordability, effectiveness, and long-term disease control have made them a first-line treatment in many chronic conditions.
This article explores the Metrex tablet uses, side effects, dosage instructions, interactions, and buying options in Pakistan. Weβll also compare Metrex vs Emthexate, discuss fertility concerns, and share important safety monitoring tips.
π©Ί What Are Metrex Tablets Used For?
Metrex tablets are a form of low-dose Methotrexate. In Pakistan, doctors primarily prescribe them for:
- Rheumatoid Arthritis
- Psoriatic Arthritis
- Severe Psoriasis
- Juvenile Idiopathic Arthritis
- Certain cancers like leukemia and lymphomas (under strict supervision)
- Ectopic pregnancy (non-surgical treatment)
π Metrex Dosage for Rheumatoid Arthritis
The usual Metrex dosage for rheumatoid arthritis ranges from 7.5 mg to 25 mg per week, taken orally. Most patients start with 2.5 mg tablets, gradually increasing the dose based on clinical response.
π‘ Important Notes:
- Taken once a week, not daily.
- Often combined with folic acid (usually 5 mg) to reduce side effects.
- Dose should always be adjusted by a rheumatologist based on blood tests and clinical symptoms.
β οΈ Methotrexate 2.5 mg Side Effects
Although generally safe when taken under supervision, methotrexate 2.5 mg side effects can affect various parts of the body.
Common Side Effects:
- Nausea
- Fatigue
- Mild hair loss
- Dizziness
Specific Concern: Mouth Ulcers
One of the more frequent complaints is mouth sores or ulcers, particularly if folic acid is not taken alongside.
Monitoring Is Essential:
Patients require routine liver and kidney monitoring, especially during long-term treatment. Blood tests should be done every 4β8 weeks.
π« Metrex and Alcohol Interaction
Combining Metrex tablets with alcohol is highly discouraged. Methotrexate can already place stress on the liver, and alcohol significantly increases the risk of hepatotoxicity or liver damage.
π©βπ©βπ¦βπ¦ Metrex and Pregnancy or Fertility Issues
Methotrexate is NOT safe during pregnancy and is classified as a teratogen. It can cause birth defects or miscarriage, and both men and women are advised to use effective contraception during and after treatment.
πΉ Female Fertility:
Women should avoid pregnancy during methotrexate use and for at least 3β6 months after stopping.
πΉ Male Fertility:
Men may experience temporary reduction in sperm count or motility.
βοΈ Drug Interactions: NSAIDs and Others
Nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen and diclofenac can increase methotrexate toxicity. Other medications such as:
- Antibiotics (e.g., penicillin)
- Proton pump inhibitors (e.g., omeprazole)
- Antiepileptics (e.g., phenytoin)
…may also interact dangerously with Metrex.
π Metrex vs Emthexate: Which One Is Better?
Both Metrex and Emthexate contain Methotrexate 2.5 mg, but they may differ in:
| Feature | Metrex | Emthexate |
|---|---|---|
| Manufacturer | Popular local brands | Common in India & PK |
| Price Range | Slightly lower | Slightly higher |
| Availability | Easily available | May need prescription |
Both are bioequivalent, so the choice usually depends on availability and cost.
πΈ Metrex 2.5 mg Price in Pakistan
The Metrex 2.5 mg price in Pakistan typically ranges between Rs. 90 to Rs. 160 per strip of 10 tablets. Prices vary by city and pharmacy, with some online platforms offering discounts.
π¦ Where to Buy Metrex Online in Pakistan
You can now conveniently order Metrex tablets online in Pakistan through verified digital pharmacies. This is especially helpful for patients in remote areas or those needing doorstep service.
π₯ Trusted Online Pharmacies:
- BrandMedic.pk
- PakMedical.pk
- HerbalMedicos.com
- Mens.pk
- Homeshop.pk
Karachi residents can benefit from fast Metrex pharmacy delivery KarachiΒ via local courier services.
π How to Take Metrex Tablets Properly
-
Weekly dose: Once per week, never daily unless prescribed specifically.
-
With or without food: Usually taken after meals to reduce stomach upset.
-
Timing: Same day and time weekly (e.g., every Monday morning).
-
Avoid other NSAIDs unless specifically allowed by your physician.
-
Folic Acid Supplementation: Always take folic acid (5 mg once or twice per week) as it helps reduce side effects like mouth ulcers and nausea.
π Metrex Monitoring Checklist
To ensure safe use of Metrex, regular blood tests are essential:
| Test Type | Frequency |
|---|---|
| Liver function tests | Every 4β8 weeks |
| Kidney function test | Every 2β3 months |
| CBC (Blood count) | Every 4β6 weeks |
Doctors may increase or reduce the dosage depending on these reports. Always share reports with your physician before continuing your next dose.
π Quick Tips for Safe Use of Metrex Tablets
- Never miss weekly doses or take them daily unless instructed
- Avoid alcohol completely
- Stay hydrated and avoid NSAIDs unless prescribed
- Report any side effects (especially ulcers or breathing issues) immediately
- Donβt use during pregnancy or while planning conception
π¬ Frequently Asked Questions (FAQs)
1. Is Metrex safe for long-term use?
Yes, under medical supervision with regular blood tests.
2. Can I take painkillers with Metrex?
Avoid over-the-counter NSAIDs unless your doctor approves.
3. Can I take Metrex during pregnancy?
No. It is not pregnancy-safe and should be stopped at least 3β6 months before planning pregnancy.
4. Is it okay to drink alcohol while on Metrex?
No. Alcohol increases the risk of liver toxicity with methotrexate.
5. How soon will I feel improvement in RA symptoms?
It usually takes 4 to 6 weeks to feel the full effect.
π§Ύ Final Words
Metrex 2.5 mg tablets are a proven and accessible solution for autoimmune diseases in Pakistan, especially rheumatoid arthritis and psoriasis. While effective, they require careful dosage control, regular monitoring, and a commitment to safe practices like avoiding alcohol and maintaining proper contraception.
Whether you’re managing RA pain, psoriasis flares, or exploring cancer care options, Metrex offers a cost-effective path to long-term symptom control when used under qualified supervision.
Make sure to buy Metrex from trusted sources, whether youβre in Karachi or elsewhere in Pakistan, and consult your doctor regularly to ensure your treatment remains safe and effective.




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